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2016年

Promotion of protein crystal growth by actively switching crystal growth mode via femtosecond laser ablation
Nature Photonics 10 723-726 (2016)
Yusuke Tominaga, Mihoko Maruyama, Masashi Yoshimura, Haruhiko Koizumi, Masaru Tachibana, Shigeru Sugiyama, Hiroaki Adachi, Katsuo Tsukamoto, Hiroyoshi Matsumura, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Hiroshi Y. Yoshikawa and Yusuke Mori


A crystallization technique for obtaining large protein crystals with increased mechanical stability using agarose gel combined with a stirring technique
J. Cryst. Growth 452 172-178 (2016)
Mihoko Maruyama, Yuki Hayashi, Hiroshi Y. Yoshikawa, Shino Okada, Haruhiko Koizumi, Masaru Tachibana, Shigeru Sugiyama, Hiroaki Adachi, Hiroyoshi Matsumura, Tsuyoshi Inoue, Kazufumi Takano, Satoshi Murakami, Masashi Yoshimura and Yusuke Mori


Molecular mechanism underlying promiscuous polyamine recognition by spermidine acetyltransferase
Int. J. Biochem. Cell Biol. 76 87-97 (2016)
Shigeru Sugiyama, Sae Ishikawa, Hideyuki Tomitori, Mayumi Niiyama, Mika Hirose, Yuma Miyazaki, Kyohei Higashi, Michio Murata, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Keiko Kashiwagi, Kazuei Igarashi and Hiroyoshi Matsumura


Protein crystallization with paper
Jpn. J. Appl. Phys. 55 050302 (2016)
Miki Matsuoka, Keisuke Kakinouchi, Hiroaki Adachi, Mihoko Maruyama, Shigeru Sugiyama, Satoshi Sano, Hiroshi Y. Yoshikawa, Yoshinori Takahashi, Masashi Yoshimura, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Kazufumi Takano


Growth of high-strength protein crystals with nanofibers
Appl. Phys. Express 9 035503 (2016)
Miki Matsuoka, Keisuke Kakinouchi, Hiroaki Adachi, Mihoko Maruyama, Shigeru Sugiyama, Iori Nakabayashi, Hiroshi Tsuchikura, Atsushi Kuwahara, Satoshi Sano, Hiroshi Y. Yoshikawa, Yoshinori Takahashi, Masashi Yoshimura, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Kazufumi Takano



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2015年

Structure, mechanism and cooperation of bacterial multidrug transporters
Curr. Opin. Struct. Biol. 33 76-91 (2015)
Dijun Du, Hendrik W van Veen, Satoshi Murakami, Klaas M Pos and Ben F Luisi


Development of protein seed crystals reinforced with high-strength hydrogels
Cryst. Eng. Comm. 17 8064-71 (2015)
Shigeru Sugiyama, Noriko Shimizu, Keisuke Kakinouchi, Osamu Hiraoka, Hiroyoshi Matsumura, Hiroshi Y. Yoshikawa, Yoshinori Takahashi, Mihoko Maruyama, Masashi Yoshimura, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Michio Murata and Yusuke Mori


Selective crystallization of metastable phase of acetaminophen by ultrasonic irradiation
Appl. Phys. Express 8 065501 (2015)
Yoichiro Mori, Mihoko Maruyama, Yoshinori Takahashi, Kenji Ikeda, Suguru Fukukita, Hiroshi Y. Yoshikawa, Shino Okada, Hiroaki Adachi, Shigeru Sugiyama, Kazufumi Takano, Satoshi Murakami, Hiroyoshi Matsumura, Tsuyoshi Inoue, Masashi Yoshimura and Yusuke Mori


Spiral Growth Can Enhance Both the Normal Growth Rate and Quality of Tetragonal Lysozyme Crystals Grown under a Forced Solution Flow
Cryst. Growth Des. 15 2137-2143 (2015)
Yuki Hayashi, Mihoko Maruyama, Masashi Yoshimura, Shino Okada, Hiroshi Y. Yoshikawa, Shigeru Sugiyama, Hiroaki Adachi, Hiroyoshi Matsumura, Tsuyoshi Inoue, Kazufumi Takano, Satoshi Murakami and Yusuke Mori


Selective crystallization of the metastable phase of indomethacin at the interface of liquid/air bubble induced by femtosecond laser irradiation
Appl. Phys. Express 8 045501 (2015)
Kenji Ikeda, Mihoko Maruyama, Yoshinori Takahashi, Yoichiro Mori, Hiroshi Y. Yoshikawa, Shino Okada, Hiroaki Adachi, Shigeru Sugiyama, Kazufumi Takano, Satoshi Murakami, Hiroyoshi Matsumura, Tsuyoshi Inoue, Masashi Yoshimura and Yusuke Mori


Preliminary X-ray analysis of the binding domain of the soybean vacuolar sorting receptor complexed with a sorting determinant of a seed storage protein
Acta Crystallogr. F71 132-5 (2015)
Nobuyuki Maruyama, Tomohiro Goshi, Shigeru Sugiyama, Mayumi Niiyama, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue,Yusuke Mori, Hiroyoshi Matsumura and Bunzo Mikam


Water-Mediated Recognition of Simple Alkyl Chains by Heart-Type Fatty-Acid-Binding Protein
Angew. Chem. Int. Ed. Engl. 54(4) 1508-11 (2015)
Shigeru Matsuoka, Shigeru Sugiyama, Daisuke Matsuoka, Mika Hirose, Sébastien Lethu, Hikaru Ano, Toshiaki Hara, Osamu Ichihara, S. Roy Kimura, Satoshi Murakami, Hanako Ishida, Eiichi Mizohata, Tsuyoshi Inoue and Michio Murata



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2014年

Crystallization and preliminary crystallographic studies of PotA, a membrane-associated ATPase of the spermidine-preferential uptake system in Thermotoga maritima
Acta Crystallogr. F70 738-741 (2014)
Shigeru Sugiyama, Keiko Kashiwagi, Keisuke Kakinouchi, Hideyuki Tomitori, Ken Kanai, Michio Murata, Hiroaki Adachi, Hiroyoshi Matsumura, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Kazuei Igarashi


A new practical technique for high quality protein crystallization with the solution stirring technique at the interface between high-concentrated hydrogel and solution
Jpn. J. Appl. Phys. 53 065502 (2014)
Yusuke Aoki, Mihoko Maruyama, Yoshinori Takahashi, Masashi Yoshimura, Hiroshi Y. Yoshikawa, Shigeru Sugiyama, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Hiroyoshi Matsumura, Tsuyoshi Inoue and Yusuke Mori


β-Lactam Selectivity of Multidrug Transporters AcrB and AcrD Resides in the Proximal Binding Pocket
J. Biol. Chem. 289 (15) 10680-90 (2014)
Naoki Kobayashi, Norihisa Tamura, Hendrik W. van Veen, Akihito Yamaguchi and Satoshi Murakami


Laser ablation for protein crystal nucleation and seeding
Chem. Soc. Rev. 43 2147-2158 (2014)
Hiroshi Y. Yoshikawa, Ryota Murai, Hiroaki Adachi, Shireru Sugiyama, Mihoko Maruyama, Yoshinori Takahashi, Kazufumi Takano, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami, Hiroshi Masuhara and Yusuke Mori



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2013年

RND efflux pumps: structural information translated into function and inhibition mechanisms
Curr. Top. Med. Chem. 13 (20) 3079-100 (2013)
Paolo Ruggerone, Satoshi Murakami, Klaas M. Pos and Attilio V. Vargiu


Structure of the human-heart fatty-acid-binding protein 3 in complex with the fluorescent probe 1-anilinonaphthalene-8-sulphonic acid
J. Synchrotron Rad. 20 923-928 (2013)
Mika Hirose, Shigeru Sugiyama, Hanako Ishida, Mayumi Niiyama, Daisuke Matsuoka, Toshiaki Hara, Eiichi Mizohata, Satoshi Murakami, Tsuyoshi Inoue, Shigeru Matsuoka and Michio Murata


Functional rotation induced by alternating protonation states in the multidrug transporter AcrB: all-atom molecular dynamics simulations
Biochemistry 52 (43) 7648-58 (2013)
Tsutomu Yamane, Satoshi Murakami and Mitsunori Ikeguchi


Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution
J. Struct. Funct. Genomics 14 (2) 71-75 (2013)
Li-Wei Hung, Heung-Bok Kim, Satoshi Murakami, Goutam Gupta, Chang-Yub Kim and Thomas C. Terwilliger


Mutation of the Mg2+ transporter SLC41A1 results in a nephronophthisis-like phenotype
J. Am. Soc. Nephrol. 24 (6) 967-977 (2013)
Toby W. Hurd, Edgar A. Otto, Eikan Mishima, Heon Yung Gee, Hana Inoue, Masato Inazu, Hideomi Yamada, Jan Halbritter, George Seki, Masato Konishi, Weibin Zhou, Tsutomo Yamane, Satoshi Murakami, Gianluca Caridi, Gianmarco Ghiggeri, Takaaki Abe and Friedhelm Hildebrandt


Drug uptake pathways of multidrug transporter AcrB studied by molecular simulations and site-directed mutagenesis experiments
J. Am. Chem. Soc. 135 (20) 7474-85 (2013)
Xin-Qui Yao, Nobuhiro Kimura, Satoshi Murakami and Shoji Takada


Expression, purification, crystallization and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli
Acta Crystallogr. F69 884-887 (2013)
Mayumi Niiyama, Shigeru Sugiyama, Mika Hirose, Sae Ishikawa, Hideyuki Tomitori, Kyohei Higashi, Tomoko Yamashita, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Michio Murata, Tsuyoshi Inoue, Yusuke Mori, Keiko Kashiwagi, Hiroyoshi Matsumura and Kazuei Igarashi


溶液流れ下におけるタンパク質の結晶成長
日本結晶成長学会誌 40 72-82 (2013)
丸山美帆子、中村真利子、佐崎 元、高橋義典、吉村政志、吉川洋史、杉山 成、安達宏昭、松村浩由、井上 豪、高野和文、村上 聡、森 勇介


A Novel Approach for Protein Crystallization by a Synthetic Hydrogel with Thermoreversible Gelation Polymer
Cryst. Growth Des. 13 1899-1904 (2013)
Shigeru Sugiyama, Noriko Shimizu, Gen Sazaki, Mika Hirose, Yoshinori Takahashi, Mihoko Maruyama, Hiroyoshi Matsumura, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue and Yusuke Mori


Effect of Gel-Solution Interface on Femtosecond Laser-Induced Nucleation of Protein
Cryst. Growth Des. 13 1491-1496 (2013)
Satoshi Nakayama, Hiroshi Y. Yoshikawa, Ryota Murai, Masateru Kurata, Mihoko Maruyama, Shigeru Sugiyama, Yusuke Aoki, Yoshinori Takahashi, Masashi Yoshimura, Seiichiro Nakabayashi, Hiroaki Adachi, Hiroyoshi Matsumura, Tsuyoshi Inoue, Kazufumi Takano, Satoshi Murakami and Yusuke Mori



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2012年

固相ハイドロゲル中でのタンパク質結晶化
日本結晶学会誌 54 300-303 (2012)
杉山成、廣瀬未果、佐崎元、安達宏昭、高野和文、村上聡、松村浩由、丸山美帆子、井上豪、森勇介


Spatially Precise, Soft Microseeding of Single Protein Crystals by Femtosecond Laser Ablation
Cryst. Growth Des. 12 4334-4339 (2012)
Hiroshi Y. Yoshikawa, Yoichiroh Hosokawa, Ryota Murai, Gen Sazaki, Tomoya Kitatani, Hiroaki Adachi, Tsuyoshi Inoue, Hiroyoshi Matsumura, Kazufumi Takano, Satoshi Murakami, Seiichiro Nakabayashi, Yusuke Mori and Hiroshi Masuhara


Effects of a Forced Solution Flow on the Step Advancement on {110} Faces of Tetragonal Lysozyme Crystals: Direct Visualization of Individual Steps under a Forced Solution Flow
Cryst. Growth Des.12 2856-2863 (2012)
Mihoko Maruyama, Hisato Kawahara, Gen Sazaki, Syou Maki, Yoshinori Takahashi, Hiroshi Y. Yoshikawa, Shigeru Sugiyama, Hiroaki Adachi, Kazufumi Takano, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami and Yusuke Mori


Growth of protein crystals in hydrogels prevents osmotic shock
J. Am. Chem. Soc.134 5786-5789 (2012)
Shigeru Sugiyama, Mihoko Maruyama, Gen Sazaki, Mika Hirose, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Hiroyoshi Matsumura



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2011年

Crystallization and preliminary X-ray crystallographic analysis of a helicase-like domain from a tomato mosaic virus replication protein
Acta Crystallogr. F67(12) 1649-1652 (2011)
Hongyu Xiang, Mayumi Niiyama, Shigeru Sugiyama, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Masayuki Ishikawa, Hiroyoshi Matsumura and Etsuko Katoh


フェムト秒レーザー誘起キャビテーションバブルによるタンパク質の結晶核発生
日本結晶成長学会誌 38 161-168 (2011)
吉川洋史、村井良多、杉山成、安達宏昭、松村浩由、井上豪、村上聡、高野和文、森勇介


Influence of energy and wavelength on femtosecond laser-induced nucleation of protein
Chemical Physics Letters 510 139-142 (2011)
Ryota Murai, Hiroshi Y. Yoshikawa, Hitoshi Hasenaka, Yoshinori Takahashi, Mihoko Maruyama, Shigeru Sugiyama, Hiroaki Adachi, Kazufumi Takano, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue and Yusuke Mori


Growth of Protein Crystals by Syringe-Type Top-Seeded Solution Growth
Cryst. Growth Des. 11 1486-1492 (2011)
Hiroyoshi Matsumura, Keisuke Kakinouchi, Tsutomu Nakamura, Shigeru Sugiyama, Mihoko Maruyama, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue and Yusuke Mori


トランスポートソーム 生体膜輸送機構の全体像に迫る 基礎、臨床、創薬応用研究の最新成果
遺伝子医学MOOK 19 57-63 (2011)
村上 聡


Laser-induced nucleation in protein crystallization: Local increase in protein concentration induced by femtosecond laser irradiation
J. Cryst. Growth 318 741-744 (2011)
Natsuko Iefuji, Ryota Murai, Mihoko Maruyama, Yoshinori Takahashi, Shigeru Sugiyama, Hiroaki Adachi, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Yuichi Koga, Kazufumi Takano and Shigenori Kanaya


結晶成長の新技術
バイオインダストリー 28 30-36 (2011)
松村浩由、杉山成、安達宏昭、高野和文、村上聡、井上豪、森勇介


Effect of Evaporation on Protein Crystals Grown in Semi-Solid Agarose Hydrogel
Jpn. J. Appl. Phys. 50 025502 1-4 (2011)
Shigeru Sugiyama, Mika Hirose, Noriko Shimizu, Mayumi Niiyama, Mihoko Maruyama, Gen Sazaki, Ryota Murai, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Hiroyoshi Matsumura


Approach for growth of high-quality and large protein crystals
J. Synchrotron Rad. 18 16-19 (2011)
Hiroyoshi Matsumura, Shigeru Sugiyama, Mika Hirose, Keisuke Kakinouchi, Mihoko Maruyama, Ryota Murai, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Yusuke Mori and Tsuyoshi Inoue



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2010年

Conformational plasticity of RNA for target recognition as revealed by the 2.15 Å crystal structure of a human IgG-aptamer complex
Nucleic Acids Res. 38 7822-9 (2010)
Yusuke Nomura, Shigeru Sugiyama, Taiichi Sakamoto, Shin Miyakawa, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Yoshikazu Nakamura and Hiroyoshi Matsumura


Drug export and allosteric coupling in a multidrug transporter revealed by molecular simulations
Nature Commun 1 117 (2010)
Xin-Qiu Yao, Hiroo Kenzaki, Satoshi Murakami and Shoji Takada


Comparison of the envelope architecture of E. coli using two methods CEMOVIS and cryo-electron tomography
J Electron Microsc 59 419-26 (2010)
Aiko Kishimoto-Okada, Satoshi Murakami, Yoshiko Ito, Noritaka Horii, Hiromitsu Furukawa, Junichi Takagi and Kenji Iwasaki


Estimated effects of silicone glue on protein crystal growth
J. Cryst. Growth 312 2771-2774 (2010)
Mihoko Maruyama, Noriko Shimizu, Shigeru Sugiyama, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Hiroyoshi Matsumura and Yusuke Mori


Crystal Growth Procedure of HIV-1 Protease-Inhibitor KNI-272 Complex for Neutron Structural Analysis at 1.9 Å Resolution
Cryst. Growth Des. 10 2990-2994 (2010)
Noriko Shimizu, Shigeru Sugiyama, Mihoko Maruyama, Yoshinori Takahashi, Motoyasu Adachi, Taro Tamada, Koushi Hidaka, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Ryota Kuroki, Yusuke Mori and Hiroyoshi Matsumura


Growth of large protein crystals by a large-scale hanging-drop method
J. Appl. Cryst. 43 937-939 (2010)
Keisuke Kakinouchi, Tsutomu Nakamura, Taro Tamada, Hiroaki Adachi, Shigeru Sugiyama, Mihoko Maruyama, Yoshinori Takahashi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Ryota Kuroki, Yusuke Mori and Hiroyoshi Matsumura


Molecular resolution investigation of tetragonal lysozyme(110) face in liquid by frequency-modulation atomic force microscopy
J. Vac. Sci. Technol. B 28 C4C11-C4C14 (2010)
Ken Nagashima, Masayuki Abe, Seizo Morita, Noriaki Oyabu, Kei Kobayashi, Hirofumi Yamada, Masahiro Ohta, Ryohei Kokawa, Ryota Murai, Hiroyoshi Matsumura, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue and Yusuke Mori


創薬バリューチェインのインシリコ技術を活用した阻害剤開発の試み
日本結晶学会誌 52 89-94 (2010)
井上豪、松村浩由、安達宏昭、森勇介、高野和文、村上聡、福西快文、中村春木、木下誉富、仲西功、奥野恭史、南方聖司、三上義明、佐久間俊広、北島正人、福岡良忠、高田俊和、坂田恒昭


Enhancement of femtosecond laser-induced nucleation of protein in a gel solution
Appl. Phys. Lett. 96 1-3 (2010)
Ryota Murai, Hiroshi Y. Yoshikawa, Yoshinori Takahashi, Mihoko Maruyama, Shigeru Sugiyama, Gen Sazaki, Hiroaki Adachi, Kazufumi Takano, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue and Yusuke Mori



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2009年

Femtosecond laser processing of protein crystals grown in agarose gel
J. Cryst. Growth 312 73-78 (2009)
Hitoshi Hasenaka, Shigeru Sugiyama, Mika Hirose, Noriko Shimizu, Tomoya Kitatani, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Hiroyoshi Matsumura


A Manipulating Tool for Protein Microcrystals in Solution Using Adhesive Materials
Jpn. J. Appl. Phys. 48 1-2 (2009)
Tomoya Kitatani, Hiroaki Adachi, Shigeru Sugiyama, Hiroyoshi Matsumura, Ryota Murai, Yoshinori Takahashi, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Kazufumi Takano


Promotion of Crystal Nucleation of Protein by Semi-Solid Agarose Gel
Appl. Phys. Express 2 1-3 (2009)
Kana Tanabe, Mika Hirose, Ryota Murai, Shigeru Sugiyama, Noriko Shimizu, Mihoko Maruyama, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Yusuke Mori, Eiichi Mizohata, Tsuyoshi Inoue and Hiroyoshi Matsumura


Growth of Large Protein Crystals by Top-Seeded Solution Growth Together with the Floating and Solution-Stirring Technique
Cryst. Growth Des. 9 5227-5232 (2009)
Noriko Shimizu, Shigeru Sugiyama, Mihoko Maruyama, Hiroshi Y. Yoshikawa, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue Hiroyoshi Matsumura and Yusuke Mori


Femtosecond Laser Processing of Agarose Gel Surrounding Protein Crystals for Development of an Automated Crystal Capturing System
Jpn. J. Appl. Phys.48 1-5 (2009)
Shigeru Sugiyama, Hitoshi Hasenaka, Mika Hirose, Noriko Shimizu, Tomoya Kitatani, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Hiroyoshi Matsumura


多剤耐性 Multi-drug resistance
Medical Science Digest 35 346-347 (2009)
村上聡


Protein Crystallization in Agarose Gel with High Strength: Developing an Automated System for Protein Crystallographic Processes
Jpn. J. Appl. Phys. 48 1-5 (2009)
Shigeru Sugiyama, Kana Tanabe, Mika Hirose, Tomoya Kitatani, Hitoshi Hasenaka, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Yusuke Mori, Tsuyoshi Inoue and Hiroyoshi Matsumura


Dynamic nature of disulfide bond formation catalysts revealed by crystal structures of DsbB
EMBO J. 28 779-791 (2009)
Keiji Inaba, Satoshi Murakami, Atsushi Nakagawa, Hiroka Iida, Mai Kinjo, Koreaki Ito and Mamoru Suzuki


Femtosecond laser-induced nucleation of protein in agarose gel
J. Cryst. Growth 311 956-959 (2009)
Hiroshi Y. Yoshikawa, Ryota Murai, Shigeru Sugiyama, Gen Sazaki, Tomoya Kitatani, Yoshinori Takahashi, Hiroaki Adachi, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue, Kazufumi Takano and Yusuke Mori



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2008年

Evaluation and Improvement of a Technique to Manipulate Protein Crystals in Solution
Jpn. J. Appl. Phys. 47 8995-8997 (2008)
Tomoya Kitatani, Hiroaki Adachi, Shigeru Sugiyama, Hiroyoshi Matsumura, Ryota Murai, Yoshinori Takahashi, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Kazufumi Takano


膜タンパク質の可溶化と調整
やさしい原理から入る タンパク質科学実験: T タンパク質をつくる ― 抽出・精製と合成 107-133 (2008)
村上聡(分担執筆)


Crystallization and preliminary X-ray crystallographic analysis of Ca2+-free primary Ca2+-sensor of Na+/Ca2+ exchanger
Acta Crystallogr. F64 1125-1127 (2008)
Masashi Mima, Chika Kawai, Kumsun Paku, Koji Tomoo, Toshimasa Ishida, Shigeru Sugiyama, Hiroshi Matsumura, Tomoya Kitatani, Hiroshi Y. Yoshikawa, Syou Maki, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Satomi Kita and Takahiro Iwamoto


Laser energy dependence on femtosecond laser-induced nucleation of protein
Appl. Phys.A 93 911-915 (2008)
Hiroshi Y. Yoshikawa, Ryota Murai, Syou Maki, Tomoya Kitatani, Shigeru Sugiyama, Gen Sazaki, Hiroaki Adachi, Tsuyoshi Inoue, Hiroyoshi Matsumura, Kazufumi Takano, Satoshi Murakami, Takatomo Sasaki and Yusuke Mori


Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272
Acta Crystallogr. F64 1003-1006 (2008)
Hiroshi Matsumura, Motoyasu Adachi, Shigeru Sugiyama, Shino Okada, Megumi Yamakami, Taro Tamada, Koushi Hidaka, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso, Tomoya Kitatani, Syou. Maki, Hiroshi Y. Yoshikawa, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Ryota Kuroki and Yusuke Mori


Functional role of transmembrane Helix 6 in drug binding and transport by the ABC transporter MsbA
Biochemistry 47 10904-10914 (2008)
Barbara Woebking, Saroj Velamakanni, Luca Federici, Markus A.Seeger, Satoshi Murakami and Hendrik van Veen


Crystallization and preliminary X-ray diffraction studies of an RNA aptamer in complex with the human IgG Fc fragment
Acta Crystallogr. F64 942-944 (2008)
Shigeru Sugiyama, Yusuke Nomura, Taiichi Sakamoto, Tomoya Kitatani, Asako Kobayashi, Shin Miyakawa, Yoshinori Takahashi, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Yoshikazu Nakamura and Hiroyoshi Matsumura


Multidrug efflux transporter, AcrB-the pumping mechanism
Curr. Opin. Struct. Biol. 18 459-465 (2008)
Satoshi Murakami


タンパク質結晶のパルスレーザー加工
OPTRONICS vol.27 No.320 153-161 (2008)
吉川洋史、村井良多、北谷友也、安達宏昭、高野和文、松村浩由、井上豪、村上聡、佐々木孝友、森勇介


フェムト秒レーザー誘起タンパク質結晶核発生
O plus E 30 480-484 (2008)
森勇介、安達宏昭、高野和文、井上豪、村上聡、松村浩由、吉川洋史


Effect of solution flow by rotary shaker on protein crystallization
J. Cryst. Growth 310 2168-2172 (2008)
Ryota Murai, Hiroshi Y. Yoshikawa, Hisato Kawahara, Syou Maki, Shigeru Sugiyama, Tomoya Kitatani, Hiroaki Adachi, Kazufumi Takano, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue, Takatomo Sasaki and Yusuke Mori


膜タンパク質の結晶化技術の新展開及び創薬バリューチェインの紹介
YAKUGAKU ZASSHI 128 497-505 (2008)
井上豪、安達宏昭、村上聡、高野和文、松村浩由、森勇介、福西快文、中村春木、木下誉富、仲西功、奥野恭史、南方聖司、下条真司、坂田恒昭


Protein crystallization in a 100 nl solution with new stirring equipment
J. Synchrotron Radiat. 15 269-272 (2008)
Syou Maki, Ryota Murai, Hiroshi Y. Yoshikawa, Tomoya Kitatani, Shinya Nakata, Hisato Kawahara,Hitoshi Hasenaka, Asako Kobayashi, Shino Okada, Shigeru Sugiyama, Hiroaki Adachi, Hiroshi Matsumura, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Takatomo Sasaki and Yusuke Mori


New Technique of Manipulating a Protein Crystal Using Adhesive Material
Appl. Phys. Express 1 1-3 (2008)
Tomoya Kitatani, Shigeru Sugiyama, Hiroyoshi Matsumura, Hiroaki Adachi, Hiroshi Y. Yoshikawa, Syou Maki, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Kazufumi Takano


フェムト秒レーザー核発生と溶液撹拌による新しいタンパク質結晶化技術
ケミカルエンジニヤリング 53 22-27 (2008)
森勇介、安達宏昭、高野和文、井上豪、村上聡、松村浩由


多剤耐性の仕組み
日本臨床 66 193-203 (2008)
村上聡


膜タンパク質の可溶化
シリーズ 生物薬科学実験講座 89-107 (2008)
村上聡(分担執筆)



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2007年

フェムト秒レーザーによるタンパク質結晶化の制御
No. RTM-07-40 7-11 (2007)
吉川洋史、村井良多、牧祥、北谷友也、杉山成、安達宏昭、高野和文、松村浩由、村上聡、井上豪、佐々木孝友、森勇介


多剤排出トランスポーターの構造と機能 結晶構造から明らかになった機能的回転メカニズム
蛋白質・核酸・酵素 52 406-414 (2007)
村上聡


Femtosecond laser-induced cleaving of protein crystal in water solution
Appl. Surf. Sci. 253 6447-6450 (2007)
Masafumi Kashii, Yoichiroh Hosokawa, Hiroshi Kitano, Hiroaki Adachi, Yusuke Mori, Kazufumi Takano, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami, Kazuomi Sugamoto, Hideki Yoshikawa, Takatomo Sasaki and Hiroshi Masuhara


Drug Development Value Chain Constructed by Collaboration Between The SOSHO Project and The NPO BIOGRID
AIP (American Inst. of Physics) Conf. Proc. 902 85-88 (2007)
Tsuyoshi Inoue, Yuji Kado, Keiji Tokuoka, Hiroyoshi Matsumura, Yasushi Kai, Yusuke Mori, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Yoshifumi Fukunishi, Haruki Nakamura, Takayoshi Kinoshita, Isao Nakanishi, Yasushi Okuno, Satoshi Minakata and Tsuneaki Sakata


Development of Protein Crystallization and Processing : Femtosecond Laser, All Solid-State 193 nm Laser, and Solution Stirring Techniques
Proceedings of SPIE 6460 1-10 (2007)
Yusuke Mori, Kazufumi Takano, Hiroaki Adachi, Tsuyoshi Inoue, Satoshi Murakami, Hiroyoshi Matsumura, Masafumi Kashii, Hiroshi Y. Yoshikawa, Syou Maki, Tomoya Kitatani, Shino Okada and Takatomo Sasaki


多剤排出トランスポーターの結晶構造解析により明らかになった機能的回転メカニズム
生物物理 47 309-316 (2007)
村上聡


多剤排出トランスポーターの構造と機能
表面科学 28 184-191 (2007)
村上聡


タンパク質結晶化技術
光学 36 10-14 (2007)
安達宏昭、森勇介、佐々木孝友、高野和文、井上豪、松村浩由、村上聡


大腸菌の異物排出トランスポーターAcrBの構造と異物認識機構
生化学 79 542-549 (2007)
村上聡


アナクロニズム
生産と技術 59 1-3 (2007)
村上聡



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2006年

タンパク質結晶構造解析入門-ブラックボックスの中身-(3)
モデリングの中身をのぞいてみよう 位相改良による電子密度図のリファイン

日本結晶学会誌 46 381-386 (2006)
村上聡


薬剤耐性化のなぞにせまる─多剤排出トランスポーターの薬剤認識・排出機構
Bionics 12月号 38-43 (2006)
村上聡


Crystal structure of the DsbB-DsbA complex reveals a mechanism of disulfide bond generation
Cell 127 789-801 (2006)
Kenji Inaba, Satoshi Murakami, Mamoru Suzuki, Atsushi Nakagawa, Eiki Yamashita, Kengo Okada and Koreaki Ito


Application of Femtosecond Laser Ablation for Detaching Grown Protein Crystals from a Glass Capillary Tube
J. Biosci. Bioeng. 102 372-374 (2006)
Masafumi Kashii, Ryo Fujisawa, Hiroaki Adachi, Yusuke Mori, Takatomo Sasaki, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami, Kazuomi Sugamoto and Hideki Yoshikawa


フェムト秒レーザー照射によるタンパク質・有機低分子の結晶化
酵素工学ニュース 56 9-13 (2006)
安達宏昭、森勇介、佐々木孝友、高野和文、松村浩由、井上豪、村上聡


細菌に薬がきかなくなる最大の“カラクリ”
Newton 11月号 (2006)
村上聡


Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Nature 443 173-179 (2006)
Satoshi Murakami, Ryosuke Nakashima, Eiki Yamashita, Takashi Matsumoto and Akihito Yamaguchi


Effect of ultrasonic irradiation on protein crystallization
J. Cryst. Growth 292 437-440 (2006)
Keisuke Kakinouchi, Hiroaki Adachi, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami, Yusuke Mori, Yuichi Koga, Kazufumi Takano and Shigenori Kanaya


Cooling-rate screening system for determining protein crystal growth conditions
J. Cryst. Growth 292 433-436 (2006)
Ryota Murai, Shinya Nakata, Masafumi Kashii, Hiroaki Adachi, Ai Niino, Kazufumi Takano, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Takatomo Sasaki


Crystallization and preliminary X-ray analysis of the tRNA thiolation enzyme MnmA from Escherichia coli complexed with tRNAGlu
Acta Crystallogr. F62 368-371 (2006)
Tomoyuki Numata, Yoshiho Ikeuchi, Shuya Fukai, Hiroaki Adachi, Hiroyoshi Matsumura, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Takatomo Sasaki, Tsutomu Suzuki and Osamu Nureki


創晶プロジェクトとバイオグリッドの連携による創薬開発の試み
SAR News 10 2-6 (2006)
井上豪、門祐示、有竹浩介、松村浩由、甲斐泰、福西快文、中村春木、木下誉富、仲西功、南方聖司、小松満男、安達宏昭、森勇介、高野和文、村上聡、佐々木孝友、宮野雅司、裏出良博、坂田恒昭


Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus
Acta Crystallogr. F62 376-380 (2006)
Tomoya Tsukazaki, Hiroyuki Mori, Shuya Fukai, Tomoyuki Numata, Anna Perederina, Hiroaki Adachi, Hiroyoshi Matsumura, Kazufumi Takano, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori, Takatomo Sasaki, Dmitry G. Vassylyev, Osamu Nureki and Koreaki Ito


フェムト秒レーザー照射による結晶核発生と溶液攪拌による新しいタンパク質結晶化技術
OPTRONICS 25 201-207 (2006)
森勇介、安達宏昭、高野和文、井上豪、村上聡、松村浩由、佐々木孝友


Solution-Stirring Method Improves Crystal Quality of Human Triosephosphate Isomerase
J. Biosci. Bioeng. 101 83-86 (2006)
Hiroaki Adachi, Ai Niino, Takayoshi Kinoshita, Masaichi Warizaya, Riyo Maruki, Kazufumi Takano, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami, Yusuke Mori and Takatomo Sasaki


Crystallization and preliminary crytallographic analysis of orotidine 5’-monophosphate decarboxylase from human malaria parasite Plasmodium falciparum
Acta Crystallogr. F62 542-545 (2006)
Sudaratana R. Krungkrai, Keiji Tokuoka, Yukiko Kusakari, Tsuyoshi Inoue, Hiroaki Adachi, Hiroyoshi Matsumura, Kazufumi Takano, Satoshi Murakami, Yusuke Mori, Yashushi Kai and Toshihiro Horii



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2005年

Protein Cryocrystallography Using Laser-Processed Crystal
Jpn. J. Appl. Phys. 44 L54-L56 (2005)
Hiroshi Kitano, Hiroyoshi Matsumura, Hiroaki Adachi, Satoshi Murakami, Kazufumi Takano, Tsuyoshi Inoue, Yusuke Mori, Masaaki Doi and Takatomo Sasaki


Effect of laser irradiation on enzyme activity
Jpn. J. Appl. Phys. 44 8216-8218 (2005)
Satoshi Murakami, Masafumi Kashii, Hiroshi Kitano, Hiroaki Adachi, Kazufumi Takano, Hiroyoshi Matsumura, Tsuyoshi Inoue, Yusuke Mori, Masaaki Doi, Kazuomi Sugamoto, Hideki Yoshikawa and Takatomo Sasaki


Semiautomatic Protein Crystallization System Featuring Crystallization Solution Preparation Function
Jpn. J. Appl. Phys. 44 6302-6303 (2005)
Hiroaki Adachi, Hiroyoshi Matsumura, Tsuyoshi Inoue, Ai Niino, Kazufumi Takano, Satoshi Murakami, Yusuke Mori and Takatomo Sasaki


Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking
Biochemistry 44 11115-11121 (2005)
Norihisa Tamura, Satoshi Murakami, Yoshiaki Oyama, Masaji Ishiguro and Akihito Yamaguchi


Processing of Membrane Protein Crystal Using UV Laser Irradiation
J. Biosci. Bioeng. 100 50-53 (2005)
Hiroshi Kitano, Satoshi Murakami, Hiroaki Adachi, Hiroyoshi Matsumura, Kazufumi Takano, Tsuyoshi Inoue, Yusuke Mori, Masaaki Doi and Takatomo Sasaki


Protein Crystal Growth Using Laser-Processed Seed Crystals
Jpn. J. Appl. Phys. 44 3177-3179 (2005)
Kengo Takeuchi, Hiroshi Kitano, Hiroaki Adachi, Yusuke Mori, Takatomo Sasaki, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami, Masaaki Doi, Yuichi Koga, Kazufumi Takano and Shigenori Kanaya


Protein Crystallization by Combining Laser Irradiation and Solution-Strring Techniques
Jpn. J. Appl. Phys. 44 1365-1366 (2005)
Hiroaki Adachi, Ai Niino, Satoshi Murakami, Kazufumi Takano, Hiroyoshi Matsumura, Takayoshi Kinoshita, Masaichi Warizawa, Tsuyoshi Inoue, Yusuke Mori and Takatomo Sasaki


Temperature-Screening System for Determining Protein Crystallization Conditions
Jpn. J. Appl. Phys. 44 4080-4083 (2005)
Hiroaki Adachi, Ai Niino, Kazufumi Takano, Hiroyoshi Matsumura, Satoshi Murakami, Tsuyoshi Inoue, Yusuke Mori and Takatomo Sasaki


Femtosecond Laser Processing of Protein Crystals in Crystallization Drop
Jpn. J. Appl. Phys. 44 L873-L875 (2005)
Masafumi Kashii, Hiroshi Kitano, Yoichiroh Hosokawa, Hiroaki Adachi, Yusuke Mori, Takatomo Sasaki, Hiroshi Masuhara, Kazufumi Takano, Hiroyoshi Matsumura, Tsuyoshi Inoue, Satoshi Murakami, Kazuomi Sugamoto and Hideki Yoshikawa


多剤耐性化を引き起こす薬剤排出タンパク質
大学と科学「タンパク質のかたちから生命の謎を解く 生物マシーナリー構造生物学の最前線」 178-190 (2005)
村上聡(分担執筆)



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2004年

Membrane Protein Crystallization Using Laser Irradiation
Jpn. J. Appl. Phys. 43 L1376-L1378 (2004)
Hiroaki Adachi, Satoshi Murakami, Ai Niino, Hiroyoshi Matsumura, Kazufumi Takano,Tsuyoshi Inoue, Yusuke Mori, Akihito Yamaguchi and Takatomo Sasaki


創晶プロジェクト
日本結晶成長学会誌 31 90-91 (2004)
安達宏昭、松村浩由、村上聡、高野和文、井上豪、森勇介、佐々木孝友


薬剤排出タンパク質の構造と機能 〜薬剤耐性化の克服を目指して
バイオサイエンスとインダストリー 62 11-16 (2004)
村上聡、山口明人


Extramembrane Central Pore of Multidrug Exporter AcrB in Escherichia coli Plays an Important Role in Drug Transport
J. Biol. Chem. 279 3743-3748 (2004)
Satoshi Murakami, Norihisa Tamura, Asami Saito, Takahiro Hirata and Akihito Yamaguchi


創晶プロジェクト〜新しいタンパク質結晶育成技術の開発〜
構造生物 10 No.2 41-54 (2004)
安達宏昭,新納愛,北野博史,村上聡,高野和文,松村浩由,井上豪,森勇介,佐々木孝友



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2003年

大腸菌多剤排出トランスポーターAcrBの結晶構造解析
日本結晶学会誌 45 256-261 (2003)
村上聡、中島良介、山下栄樹、山口明人


Multidrug-exporting secondary transporters
Curr.Opin. Struct. Biol. 13 443-452 (2003)
Satoshi Murakami and Akihito Yamaguchi


大腸菌多剤排出トランスポーターのX線結晶構造解析
放射光 16 204-212 (2003)
村上聡、 中島良介、山下栄樹、山口明人


多剤排出トランスポーターAcrBの結晶構造解析
生物工学. 81 155-160 (2003)
村上聡、 中島良介、山下栄樹、山口明人


異物排出トランスポーターの結晶構造、ついに決まる。
蛋白質・核酸・酵素 48 26-32 (2003)
村上聡、山口明人



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2002年

多剤排出トランスポーターAcrBの結晶構造解析
細胞工学 21 1520-1521 (2002)
村上聡、山口明人


Crystal structure of bacterial multidrug efflux transporter AcrB
Nature 419 587-593 (2002)
Satoshi Murakami, Ryosuke Nakashima, Eiki Yamashita and Akihito Yamaguchi



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2001年

Monoclonal antibody that binds to the central loop of the Tn10-encoded metal tetracycline/H+ antiporter of Escherichia coli
J Biochem. 129 87-91 (2001)
Shigeyuki Nada, Satoshi Murakami, Shizuka Okamoto, Yoshiyuki Kubo and Akihito Yamaguchi



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1998年

Crystals of bovine heart ubiquinol-cytochrome c reductase diffracting X-rays up to 2.8 Å resolution at 276 K
Acta Crystallogr D54 146-147 (1998)
Satoshi Murakami, Shinzawa-Itoh Kyoko and Shinya Yoshikawa



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